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HCUP consists of multiple databases; however, the database used in this study was the Nationwide Inpatient Sample NIS for the years andwhich includes rodrigo renno, patients.

This database rodrigo renno inpatient data from over hospitals and up to rodrigo renno states in the United States. The study included individuals who were at least 18 years of age and had an ICD-9 diagnosis code for SSc.

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The NIS database allows up to 25 diagnoses per patient. Controls were excluded if they had one or more ICD-9 diagnosis codes for over different autoimmune diseases or were under the age of SSc patients and controls rodrigo renno randomized and matched by age and sex.

Four controls were matched to each SSc patient 13, SSc and 54, controls. The comorbid conditions used in this analysis totaled 25 and were variables included rodrigo renno the NIS database obtained from the AHRQ comorbidity software.

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This comorbidity software assigns variables that identify comorbidities in discharge records using ICDCM codes. Statistical analysis All statistical analyses were conducted using SAS version 9. Logistic regression models were used to compare patients with and without SSc for 25 different rodrigo renno.

The survey logistic procedures were used in this analysis to include the weight variable provided in the database.


The presence of SSc was used as the dependent variable in these models. The majority of rodrigo renno admitted were white females admitted to hospitals in urban locations.


In each year, patients admitted with SSc as principal diagnosis were significantly younger than patients admitted with SSc as secondary diagnosis.

Table 1 Hospital rodrigo renno with systemic sclerosis SSc as principal or secondary diagnosis by demographics and year of admission Table 2 shows the baseline characteristics of SSc patients and controls.

Comparisons of demographic variables for SSc patients and controls revealed equal distributions for age and sex.

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On the other hand, there were significantly more blacks rodrigo renno the SSc group. The SSc group also had more admissions to hospitals in urban locations. The prevalence of GI manifestations included in our analysis was Esophageal reflux constituted the major GI manifestation experienced by SSc patients, with a prevalence of Other significantly elevated GI manifestations in SSc patients included dysphagia 4.

On the other hand, cholelithiasis was found to be significantly rodrigo renno common in SSc patients 1. There was no significant association between SSc and diverticulosis, peptic ulcer disease or other gallbladder diseases.

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Table 3 Distribution of selected gastrointestinal disorders between patients with and without systemic sclerosis SSc Table 4 lists the frequencies of a broad rodrigo renno of GI malignancies among SSc and non-SSc patients.

Analysis by type of cancer showed significantly lower frequency of colon 0.


No significant difference between groups was seen in other GI malignancies, including esophageal, gastric and gallbladder malignancies. Table 4 Distribution of gastrointestinal malignancies between patients with and without rodrigo renno sclerosis Rodrigo renno Discussion This study aimed to examine the prevalence of GI manifestations among SSc patients, based on hospital admissions data, and also to investigate the association between GI manifestations and SSc compared to controls.

The prevalence of GI manifestations among SSc patients included in our analysis was GI manifestations are known to be significantly more common in SSc patients [ 4 ].